Acute On Chronic Liver Failure Market Drugs, Insights and Market Analysis

September 24 20:20 2020
Acute On Chronic Liver Failure Market Drugs, Insights and Market Analysis

(Albany, US) DelveInsight has launched a new report on Acute on Chronic Liver Failure Market

 

DelveInsight’s “Acute On Chronic Liver Failure (ACLF) – Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Acute On Chronic Liver Failure (ACLF) , historical and forecasted epidemiology as well as the Acute On Chronic Liver Failure (ACLF) market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. The Acute On Chronic Liver Failure (ACLF) market report provides current treatment practices, emerging drugs, Acute On Chronic Liver Failure (ACLF) market share of the individual therapies, current and forecasted Acute On Chronic Liver Failure (ACLF) market Size from 2017 to 2030 segmented by seven major markets. The Report also covers current Acute on Chronic Liver Failure (ACLF) treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

 

The term Acute-on-Chronic Liver Failure (ACLF) was first introduced in 1995 to describe a condition in which two “lesions” or “insults” act simultaneously on the liver, one of which is chronic and the other is acute. However, the universally accepted and used definition of ACLF is still lacking. Thus, several definitions have been developed by expert groups from the American Association for the Study of Liver Diseases (AASLD), European Association for the Study of the Liver (EASL), and Asian-Pacific Association for the Study of the Liver (APASL). According to AASLD and EASL working group ACLF is, “Acute deterioration of pre-existing chronic liver disease usually related to a precipitating event and associated with increased mortality at 3-months due to multi-system organ failure”. On the other hand, the group of experts from APASL define the ACLF as, “Acute liver injury manifesting as jaundice (serum bilirubin ≥5 mg/dL) and coagulopathy (INR ≥1.5 or prothrombin activity of <40%), complicated within 4 weeks by ascites and/or encephalopathy in a patient previously diagnosed or undiagnosed chronic liver diseases.”

 

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Acute on Chronic Liver Failure Market

Currently, there is no specific effective treatment available for patients with ACLF, and therefore, treatment is based on organ support and treatment of associated complications. Central to the treatment of ACLF is early diagnosis and control of the precipitating factor. The main principles of management in these patients are to provide support to each of the organs with failure and to promote recovery of the hepatic gland. The current treatment includes the use of Devices for detoxification, Antiviral therapy and Liver transplantation.

 

Acute on Chronic Liver Failure Treatment

Moreover, due to its multifactorial nature, a single therapeutic action would not be effective in reversing the disease. Considering that currently there is no specific treatment for ACLF, research should be based on potential new treatments addressed to pathophysiological mechanisms. To fulfill the current unmet need, the field of ACLF has moved very rapidly in the past 5 years. The availability of a large volume of published data from the East and the West has allowed reassessing the initial definitions. And attempts to abrogate, ameliorate, or reverse the ongoing injury would allow the return of hepatic synthetic functions and reversal of the liver damage. Early predictors of mortality and non-reversibility of the condition would pave the way to offer priority liver transplantation to such patients.

 

Acute on Chronic Liver Failure Report Scope

  • The report covers the descriptive overview of Acute On Chronic Liver Failure (ACLF) , explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
  • Comprehensive insight has been provided into the Acute On Chronic Liver Failure (ACLF) epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for Acute On Chronic Liver Failure (ACLF) are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
  • A detailed review of Acute On Chronic Liver Failure (ACLF) market; historical and forecasted is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Acute on Chronic Liver Failure (ACLF) market.

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Table of content

1. Key Insights

2. Executive Summary of Acute On Chronic Liver Failure (ACLF)

3. Competitive Intelligence Analysis for Acute On Chronic Liver Failure (ACLF)

4. Acute On Chronic Liver Failure (ACLF): Market Overview at a Glance

5. Acute On Chronic Liver Failure (ACLF): Disease Background and Overview

6. Patient Journey

7. Acute On Chronic Liver Failure (ACLF) Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Unmet Needs

10. Key Endpoints of Acute On Chronic Liver Failure (ACLF) Treatment

11. Marketed Products

12. Emerging Therapies

13. Acute On Chronic Liver Failure (ACLF): Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Acute On Chronic Liver Failure (ACLF)

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight

 

Why should you buy this report?

  • The report will help in developing business strategies by understanding trends shaping and driving the Acute On Chronic Liver Failure (ACLF) market
  • To understand the future market competition in the Acute On Chronic Liver Failure (ACLF) market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Acute On Chronic Liver Failure (ACLF) in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Acute On Chronic Liver Failure (ACLF) market
  • To understand the future market competition in the Acute On Chronic Liver Failure (ACLF) market.

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